Drug Resistant Epilepsy
Drug-resistant epilepsy (also called refractory or intractable epilepsy) is when seizures continue despite trying two or more appropriate anti-seizure medications.
Prevalence
Studies show that about one-third of adults and roughly 20–25% of children with epilepsy do not achieve seizure control with medications.
Causes
Can be due to underlying brain conditions (ex. genetic factors, brain injuries, structural abnormalities) or unknown reasons.
Impact
Uncontrolled seizures increase risks of SUDEP, injury, learning problems, intellectual disability, emotional and behavioral problems, and increased risk from side effects due to multiple antiseizure medications.
Alternative Treatments
Some options include diet change (Keto, Modified Atkins, or Low-Glycemic Index), Vagus Nerve Stimulation (VNS), Responsive Neurostimulation (RNS) or Deep Brain Stimulation, epilepsy surgery, immunotherapy, and clinical trials for new treatments.
Quality of Life Considerations
While some people find success with alternative treatments, others may continue to experience seizures despite interventions.
Who Can Help?
For the best care, seek an epilepsy center and Epileptologist —these are specialized clinics and doctors with a team approach to managing drug-resistant epilepsy.
always consult a healthcare professional